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(E)-AG 556
$60 – $300
Products Details
Product Description
– (E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production[1][2].
Web ID
– HY-101041
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H20N2O3
References
– [1]George J, et al. Tyrphostin AG-556 reduces myocardial infarct size and improves cardiac performance in the rat. Exp Mol Pathol. 2003 Jun;74(3):314-8.|[2]Gazit A, et al. Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J Med Chem. 1991 Jun;34(6):1896-907.
CAS Number
– 133550-41-1
Molecular Weight
– 336.39
Compound Purity
– 99.92
SMILES
– O=C(NCCCCC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
