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Products Details
Product Description
– Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].
Web ID
– HY-145708
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C26H25NO4
References
– [1]Ekström F, et al. Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. ACS Med Chem Lett. 2022, 13(3):499-506.
CAS Number
– 1801157-64-1
Molecular Weight
– 415.48
SMILES
– O=C1OC2=C(C(CO)=C1)C=CC(OCC3=CC=C(CN(CC4=CC=CC=C4)C)C=C3)=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE);Monoamine Oxidase
Isoform
– AChE;MAO-B
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
