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Doxorubicinol
SKU
HY-121259-Get quote
Category Reference compound
Tags Cardiovascular Disease, Endogenous Metabolite, Metabolic Enzyme/Protease
Products Details
Product Description
– Doxorubicinol, a potent inhibitor of the cardiac sarcoplasmic reticulum calcium pump, inhibits systolic myocardial function in isolated heart muscle. Doxorubicinol inhibits tumor cell growth and has cardiotoxicity.
Web ID
– HY-121259
Shipping
– Room temperature
Molecular Formula
– C27H31NO11
References
– [1]Olson RD, et al. Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol. Proc Natl Acad Sci U S A. 1988 May;85(10):3585-9.
CAS Number
– 54193-28-1
Molecular Weight
– 545.54
SMILES
– O=C1C2=C(C3=C(C(O)=C2C(C4=C1C=CC=C4OC)=O)[C@@H](O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C[C@](O)([C@H](CO)O)C3)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.