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Doxorubicin-SMCC
$150 – $1,450
Products Details
Product Description
– Doxorubicin-SMCC is a agent-linker conjugate for ADC. Doxorubicin-SMCC contains a non-cleavable ADC linker and a DNA topoisomerase II inhibitor Doxorubicin[1].
Web ID
– HY-116063
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C39H42N2O14
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 400647-59-8
Molecular Weight
– 762.76
Compound Purity
– 99.48
SMILES
– C[C@@H]1O[C@H](C[C@@H]([C@@H]1O)NC(C2CCC(CC2)CN3C(C=CC3=O)=O)=O)O[C@H]4C[C@](O)(C(CO)=O)CC5=C(O)C(C(C6=C7C(OC)=CC=C6)=O)=C(C7=O)C(O)=C45
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Drug-Linker Conjugates for ADC
Isoform
– Daunorubicins/Doxorubicins
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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