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Donafenib
Price range: 134 CAD through 1,840 CAD
Products Details
Product Description
– Donafenib(Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
Web ID
– T16909
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H13ClD3F3N4O3
References
– Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109.
CAS Number
– 1130115-44-4
Molecular Weight
– C21H13ClD3F3N4O3
Compound Purity
– 0.9988
SMILES
– [2H]C([2H])([2H])NC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
Target
– ADC Linker
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis|||MAPK
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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