Diphylline

$79$238

Products Details

Product Description

– Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema[1][2].

Web ID

– HY-B0128

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C10H14N4O4

References

– [1]Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.|[2]Yosry El-said, et al. In-vitro evaluation of sustained-release dyphylline tablets. Drug Development and Industrial Pharmacy. Volume 17, 1991 – Issue 2

CAS Number

– 479-18-5

Molecular Weight

– 254.24

Compound Purity

– 99.25

SMILES

– O=C(N1C)N(C)C2=C(N(CC(O)CO)C=N2)C1=O

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)

Target

– Adenosine Receptor;Phosphodiesterase (PDE)

Pathway

– GPCR/G Protein;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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