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Diphylline
SKU
HY-B0128-100 mg
Category Reference compound
Tags Adenosine Receptor;Phosphodiesterase (PDE), GPCR/G Protein;Metabolic Enzyme/Protease, Inflammation/Immunology; Cardiovascular Disease
$79 – $238
Products Details
Product Description
– Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema[1][2].
Web ID
– HY-B0128
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H14N4O4
References
– [1]Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.|[2]Yosry El-said, et al. In-vitro evaluation of sustained-release dyphylline tablets. Drug Development and Industrial Pharmacy. Volume 17, 1991 – Issue 2
CAS Number
– 479-18-5
Molecular Weight
– 254.24
Compound Purity
– 99.25
SMILES
– O=C(N1C)N(C)C2=C(N(CC(O)CO)C=N2)C1=O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)
Target
– Adenosine Receptor;Phosphodiesterase (PDE)
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Reference compound
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