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Diphylline
$79 – $238
Products Details
Product Description
– Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema[1][2].
Web ID
– HY-B0128
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H14N4O4
References
– [1]Schwabe U, et al. Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.|[2]Yosry El-said, et al. In-vitro evaluation of sustained-release dyphylline tablets. Drug Development and Industrial Pharmacy. Volume 17, 1991 – Issue 2
CAS Number
– 479-18-5
Molecular Weight
– 254.24
Compound Purity
– 99.25
SMILES
– O=C(N1C)N(C)C2=C(N(CC(O)CO)C=N2)C1=O
Clinical Information
– Launched
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)
Target
– Adenosine Receptor;Phosphodiesterase (PDE)
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
