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Dimethylamiloride (hydrochloride)

Products Details

Product Description

– Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research[1].

Web ID

– HY-132181

Shipping

– Room temperature

Molecular Formula

– C8H13Cl2N7O

References

– [1]Masereel B, et al. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54.

CAS Number

– 2235-97-4

Molecular Weight

– 294.14

SMILES

– O=C(C1=NC(Cl)=C(N(C)C)N=C1N)NC(N)=N.Cl

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Na+/H+ Exchanger (NHE)

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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