DHODH-IN-8

SKU T11030-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 187 CAD through 1,808 CAD

Products Details

Product Description

– DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively.

Web ID

– T11030

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H13ClN2O2

References

– Davies M, et al. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93.

CAS Number

– 1148126-03-7

Molecular Weight

– C17H13ClN2O2

Compound Purity

– 0.9957

SMILES

– ClC1=C(C2=CC=C(NC(/C(=C(/C)O)/C#N)=O)C=C2)C=CC=C1

Target

– ADC Linker

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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