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Deoxycholic acid
$66 – $92
Products Details
Product Description
– Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2].
Web ID
– HY-N0593
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H40O4
Citations
– Aquaculture. 2023 Sep 18, 740123.|Cancer Cell Int. 2019 Jan 31;19:24.|Cell Death Discov. 2020 Jul 6;6:56.|Cell Res. 2019 Mar;29(3):193-205. |Drug Metab Dispos. 2021 May;49(5):369-378.|J Invest Dermatol. 19 November 2021.|Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.|Microbiome. 2019 Mar 20;7(1):43. |R Soc Open Sci. 2020 Jul 8;7(7):200635.|Nat Cell Biol. 2018 Oct;20(10):1145-1158.
References
– [1]Somm E, et al. β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue. JCI Insight. 2017 Apr 20;2(8). pii: 91809.|[2]Wang X, et al. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in micedependent on c-Myc expression. Cancer Med. 2017 Apr;6(4):788-797.
CAS Number
– 83-44-3
Molecular Weight
– 392.57
Compound Purity
– 99.82
SMILES
– C[C@@]1([C@@]2([H])[C@H](C)CCC(O)=O)[C@](CC2)([H])[C@@](CC[C@@]3([H])[C@@]4(CC[C@@H](O)C3)C)([H])[C@]4([H])C[C@@H]1O
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Endogenous Metabolite;G protein-coupled Bile Acid Receptor 1
Isoform
– Human Endogenous Metabolite;Microbial Metabolite
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
