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Products Details
Product Description
– DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].
Web ID
– T17775
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H20N2O5
References
– Silvie A. Meeuwissen, et al. Copper-free click chemistry on polymersomes: pre- vs. post-self-assembly functionalization. Polymer Chemistry. 2012, 3: 1783-1795.
CAS Number
– 1393350-27-0
Molecular Weight
– C24H20N2O5
SMILES
– O=C(ON1C(=O)CCC1=O)CCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
Target
– Others
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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