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Dapiprazole (hydrochloride)
SKU
HY-A0142A-10 mg
Category Reference compound
Tags Adrenergic Receptor, Endocrinology, GPCR/G Protein;Neuronal Signaling
$35 – $250
Products Details
Product Description
– Dapiprazole hydrochloride is a potent, selective and orally active alpha-1 adrenoceptor antagonist. Dapiprazole hydrochloride suppresses the opioid withdrawal symptoms. Dapiprazole hydrochloride is also used as eye drops for reversing mydriasis[1][2][3].
Web ID
– HY-A0142A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C19H28ClN5
References
– [1]Hou RH, et al. Arousal and the pupil: why diazepam-induced sedation is not accompanied by miosis. Psychopharmacology (Berl). 2007 Nov;195(1):41-59.|[2]Valeri P, et al. Effects of dapiprazole, clonidine and yohimbine on the development of dependence and withdrawal behaviour in mice. Drug Alcohol Depend. 1989 Jan;23(1):73-7.|[3]Allinson RW, et al. Reversal of mydriasis by dapiprazole. Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
CAS Number
– 72822-13-0
Molecular Weight
– 361.91
Compound Purity
– 99.87
SMILES
– CC1=CC=CC=C1N2CCN(CCC3=NN=C4CCCCN43)CC2.[H]Cl
Clinical Information
– Launched
Research Area
– Endocrinology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 100 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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