Dapansutrile

SKU T15052-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 66 CAD through 1,512 CAD

Products Details

Product Description

– Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.

Web ID

– T15052

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C4H7NO2S

Citations

– 1. Tai G J, Ma Y J, Feng J L, et al.NLRP3 inflammasome-mediated premature immunosenescence drives diabetic vascular aging dependent on the induction of perivascular adipose tissue dysfunction.Cardiovascular Research.2024: cvae079.

References

– Alba Sánchez-Fernández, Skouras D B , Dinarello C A , et al. OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis[J]. Frontiers in Immunology, 2019, 10.

CAS Number

– 54863-37-5

Molecular Weight

– C4H7NO2S

Compound Purity

– ≥98%

SMILES

– CS(=O)(=O)CCC#N

Target

– Others

Pathway

– NF-κB|||Immunology/Inflammation

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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