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Dapagliflozin
Price range: 67 CAD through 245 CAD
Products Details
Product Description
– Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.
Web ID
– T2389
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H25ClO6
Citations
– 1. Xuan M Y, Piao S G, Ding J, et al. Dapagliflozin Alleviates Renal Fibrosis by Inhibiting RIP1-RIP3-MLKL-Mediated Necroinflammation in Unilateral Ureteral Obstruction. Frontiers in pharmacology. 2021, 12
2. Ding L, Chen X, Zhang W, et al.Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling.The Journal of Clinical Investigation.2023, 133(1).
3. Huang H, Kung F L, Huang Y W, et al.Sensitization of cancer cells to paclitaxel-induced apoptosis by canagliflozin.Biochemical Pharmacology.2024: 116140.
References
– Chang YK, et al. Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury. PLoS One. 2016 Jul 8;11(7):e0158810.
CAS Number
– 461432-26-8
Molecular Weight
– C21H25ClO6
Compound Purity
– 0.9982
SMILES
– O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2
Pathway
– GPCR/G Protein|||Angiogenesis|||Chromatin/Epigenetic
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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