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Dapagliflozin-3-O-β-D-Glucuronide
Price range: 565 CAD through 1,069 CAD
Products Details
Product Description
– Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A9 to dapagliflozin-3-O-β-D-glucuronide, which is 2,600-fold less potent than the parent compound with regard to SGLT2 inhibition.[2]
Web ID
– T35619
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H33ClO12
References
– Chao, E.C., and Henry, R.R. SGLT2 inhibition – A novel strategy for diabetes treatment. Nature Reviews.Drug Discovery 9(7), 551-559 (2010).
CAS Number
– 1351438-75-9
Molecular Weight
– C27H33ClO12
SMILES
– O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C3=CC(CC4=CC=C(OCC)C=C4)=C(Cl)C=C3
Target
– Gamma-secretase
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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