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Dacarbazine
$38 – $132
Products Details
Product Description
– Dacarbazine is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/ml, respectively. Dacarbazine can be used for the research of metastatic malignant melanoma[1][2].
Web ID
– HY-B0078
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C6H10N6O
References
– [1]Al-Badr AA, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol. 2016;41:323-77. |[2]Rojo JM, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29(5):345-51.|[3]Serrone, L., et al., Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview. J Exp Clin Cancer Res, 2000. 19(1): p. 21-34.
CAS Number
– 4342-03-4
Molecular Weight
– 182.18
Compound Purity
– 99.96
SMILES
– O=C(C1=C(/N=N/N(C)C)NC=N1)N
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 1 mg/mL (ultrasonic;warming)
Target
– Apoptosis;Nucleoside Antimetabolite/Analog
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
