D-Serine

$55$77

Products Details

Product Description

– D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration[1][2].

Web ID

– HY-100808

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C3H7NO3

References

– [1]Andrea R. Durrant, et al. D-Serine in Neuropsychiatric Disorders: New Advances.|[2]MacKay MB, et al. D-Serine: Potential Therapeutic Agent and/or Biomarker in Schizophrenia and Depression? Front Psychiatry. 2019 Feb 6;10:25.|[3]Dai X, et al. D-Serine made by serine racemase in Drosophila intestine plays a physiological role in sleep. Nat Commun. 2019 May 7;10(1):1986.|[4]Suwandhi L, et al. Chronic d-serine supplementation impairs insulin secretion. Mol Metab. 2018 Oct;16:191-202.

CAS Number

– 312-84-5

Molecular Weight

– 105.09

Compound Purity

– 98.0

SMILES

– N[C@H](CO)C(O)=O

Clinical Information

– Launched

Research Area

– Neurological Disease

Solubility

– H2O : ≥ 50 mg/mL|Methanol : < 1 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Endogenous Metabolite;iGluR

Isoform

– Human Endogenous Metabolite;NMDA Receptor

Pathway

– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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