D-erythro-MAPP

$250$425

Products Details

Product Description

– D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro[1].

Web ID

– HY-137422

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C23H39NO2

References

– [1]Hüseyin İzgördü, et al. Characteristics of apoptosis induction in human breast cancer cells treated with a ceramidase inhibitor. Cytotechnology. 2020 Dec;72(6):907-919.|[2]A Bielawska, et al. (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase. J Biol Chem. 1996 May 24;271(21):12646-54.

CAS Number

– 143492-38-0

Molecular Weight

– 361.56

Compound Purity

– 98.0

SMILES

– O[C@@H](C1=CC=CC=C1)[C@@H](C)NC(CCCCCCCCCCCCC)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Ceramidase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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