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D-Cl-amidine (hydrochloride)
SKU
HY-100574D-10 mg
Category Reference compound
Tags Apoptosis;Epigenetics, Apoptosis;Protein Arginine Deiminase, Cancer
$250 – $1,800
Products Details
Product Description
– D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
Web ID
– HY-100574D
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H20Cl2N4O2
References
– [1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3(12):1081-1085.
Molecular Weight
– 347.24
Compound Purity
– 99.40
SMILES
– O=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 80 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;Protein Arginine Deiminase
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.