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Cytarabine
Price range: 48 CAD through 176 CAD
Products Details
Product Description
– Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
Web ID
– T1272
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C9H13N3O5
Citations
– 1. He S, Li Y, Shi X, et al.DNA methylation landscape reveals LIN7A as a decitabine-responsive marker in patients with t (8; 21) acute myeloid leukemia.Clinical Epigenetics.2023, 15(1): 1-13.
2. Islam S, Rahaman M H, Yu M, et al.Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition.Cancers.2023, 15(4): 1044.
3. Zhao Y, Zhao N, Cai Y, et al.An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo.Frontiers in Cellular and Infection Microbiology.2022, 12: 1813.
4. Thieulent C, Hue E, Sutton G, et al. Identification of antiviral compounds against equid herpesvirus-1 using real-time cell assay screening: efficacy of decitabine and valganciclovir alone or in combination. Antiviral Research. 2020: 104931
5. Wang B, He B S, Ruan X L, et al. An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening. Military Medical Research. 2022, 9(1): 1-17.
6. Wang B, Pei J, Zhang H, et al.Dihydropyridine-derived calcium channel blocker as a promising anti-hantavirus entry inhibitor.Interventions for emerging infectious diseases.2023, 16648714.
7. He S, Li Y, Wang L, et al.DNA methylation landscape reveals GNAS as a decitabine-responsive marker in patients with acute myeloid leukemia.Neoplasia.2024, 49: 100965.
8. Small S H, Perez R E, Beauchamp E M, et al.Targeting SLFN11-Regulated Pathways Restores Chemotherapy Sensitivity in AML.Blood Neoplasia.2024: 100037.
9. The TRPV1-PKM2-SREBP1 axis maintains microglial lipid homeostasis in Alzheimer’s disease[J]. Cell Death & Disease, 2025, 16(1): 14.
References
– Desai UN, et al. Enhancement of the cytotoxic effects of Cytarabine in synergism with Hesperidine and Silibinin in Acute Myeloid Leukemia: An in-vitro approach. J Cancer Res Ther. 2015 Apr-Jun;11(2):352-7.
CAS Number
– 147-94-4
Molecular Weight
– C9H13N3O5
Compound Purity
– 0.9992
SMILES
– O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)C=C2
Target
– Others
Pathway
– Apoptosis|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Autophagy|||Metabolism|||Microbiology/Virology
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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