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CU-CPT9b
$150 – $1,200
Products Details
Product Description
– CU-CPT9b is a specific TLR8 antagonist, with an IC50 of 0.7 nM. CU-CPT9b shows high binding affinity towards TLR8 with a Kd of 21 nM[1].
Web ID
– HY-112051
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H13NO2
References
– [1]Zhang S, et al. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018 Jan;14(1):58-64.
CAS Number
– 2162962-69-6
Molecular Weight
– 251.28
Compound Purity
– 99.03
SMILES
– OC1=C(C)C=C(C=C1)C2=CC=NC3=CC(O)=CC=C32
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– Toll-like Receptor (TLR)
Isoform
– TLR8
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
