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Products Details
Product Description
– CTP Synthetase-IN-1 is a potent, orally active cytidine 5′-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects[1].
Web ID
– HY-152149
Shipping
– Room temperature
Molecular Formula
– C20H19F3N6O3S2
References
– [1]Andrew Novak, et al. Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation. J Med Chem. 2022 Dec 22;65(24):16640-16650.
CAS Number
– 2338811-71-3
Molecular Weight
– 512.53
SMILES
– O=C(C(C)(C)C1=CSC(NS(=O)(C2CC2)=O)=N1)NC3=NC=C(C4=NC(C(F)(F)F)=CN=C4)C=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
