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Product Description
– Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate (NSC-49420) diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators.
Web ID
– T0034
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H30O6
References
– Grossman R, et al. Ann N Y Acad Sci. 2006, 1071:410-21.
CAS Number
– 50-04-4
Molecular Weight
– C23H30O6
Compound Purity
– 0.9863
SMILES
– [H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
Target
– Glucocorticoid Receptor|||Endogenous Metabolite
Pathway
– Metabolism|||Endocrinology/Hormones
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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