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Clopamide
$50 – $80
Products Details
Product Description
– Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. Clopamide has the potential for hypertension and cardiac failure research[1][2].
Web ID
– HY-B1477
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C14H20ClN3O3S
References
– [1] J J McNeil, et al. Clopamide: plasma concentrations and diuretic effect in humans. Clin Pharmacol Ther. 1987 Sep;42(3):299-304.|[2]Yoshiteru Noutoshi, et al. Diuretics prime plant immunity in Arabidopsis thaliana. PLoS One. 2012;7(10):e48443.|[3]B Odlind, et al. Renal tubular secretion and effects of chlorothiazide, hydrochlorothiazide and clopamide: a study in the avian kidney. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):187-97.|[4]E Müller-Schweinitzer, et al. Interaction of cyclosporine-A with the renin-angiotensin system in canine veins. Naunyn Schmiedebergs Arch Pharmacol. 1989 Aug;340(2):252-7.
CAS Number
– 636-54-4
Molecular Weight
– 345.84
Compound Purity
– 98.30
SMILES
– O=C(NN1[C@H](C)CCC[C@@H]1C)C2=CC=C(Cl)C(S(=O)(N)=O)=C2
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Cardiovascular Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Sodium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
