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Clomipramine (hydrochloride)
$79 – $119
Products Details
Product Description
– Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].
Web ID
– HY-B0457
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H24Cl2N2
References
– [1]Yumi Sugimoto, et al. The tricyclic antidepressant Clomipramine increases plasma glucose levels of mice. J Pharmacol Sci. 2003 Sep;93(1):74-9.|[2]Mushtaq Ahmed, et al. Comparative study of the inhibitory effect of antidepressants on cholinesterase activity in <i>Bungarus sindanus</i> (krait) venom, human serum and rat striatum. J Enzyme Inhib Med Chem. 2008 Dec;23(6):912-7.|[3]Federica Cavaliere,The tricyclic antidepressant Clomipramine inhibits neuronal autophagic flux. Sci Rep. 2019 Mar 19;9(1):4881.
CAS Number
– 17321-77-6
Molecular Weight
– 351.31
Compound Purity
– 99.14
SMILES
– CN(C)CCCN1C2=CC(Cl)=CC=C2CCC3=C1C=CC=C3.Cl
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
Target
– Serotonin Transporter
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
