![](https://immunomart.com/wp-content/uploads/2024/06/HY-B0457AS.gif)
Download Files:
Clomipramine-d3
SKU
HY-B0457AS-10mg
Category Isotope-Labeled Compounds
Tags Dopamine Receptor;Isotope-Labeled Compounds;Serotonin Transporter, GPCR/G Protein;Neuronal Signaling;Others, Neurological Disease
Products Details
Product Description
– Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
Web ID
– HY-B0457AS
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H20D3ClN2
References
– [1]McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53.|[2]Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22.
CAS Number
– 136765-29-2
Molecular Weight
– 317.87
SMILES
– ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C([2H])([2H])[2H])C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor;Isotope-Labeled Compounds;Serotonin Transporter
Isoform
– D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.