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Citalopram (hydrobromide)
$42 – $145
Products Details
Product Description
– Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM. Antidepressant effect[1].
Web ID
– HY-B1287
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H22BrFN2O
Citations
– Eur J Pharmacol. 2018 Sep 27;841:57-66.|J Clin Psychopharmacol. 2021 Jun 11.|Neurochem Int. 2019 Dec;131:104552.|Pharmacol Res Perspect. 2020 Apr;8(2):e00575.|Research Square Preprint. 2021 Feb.|Comput Struct Biotechnol J. 2023 Jul 7, 21, 3490-3502.
References
– [1]J Hyttel. Citalopram–pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(3):277-95.|[2]Laurent Sakka, et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8(26):42789-42807.|[3]F Pollier, et al. Serotonin reuptake inhibition by citalopram in rat strains differing for their emotionality. Neuropsychopharmacology. 2000 Jan;22(1):64-76.
CAS Number
– 59729-32-7
Molecular Weight
– 405.30
Compound Purity
– 99.74
SMILES
– N#CC1=CC2=C(C(C3=CC=C(F)C=C3)(CCCN(C)C)OC2)C=C1.[H]Br
Clinical Information
– Launched
Research Area
– Neurological Disease; Cancer
Solubility
– DMSO : ≥ 38 mg/mL|H2O : 10 mg/mL (ultrasonic)
Target
– Autophagy;Serotonin Transporter
Pathway
– Autophagy;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
