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Cinchonidine
SKU
HY-N0173-100 mg
Category Natural Products
Tags Anti-infection;Neuronal Signaling, Infection, Parasite;Serotonin Transporter
$50 – $55
Products Details
Product Description
– Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities[1].
Web ID
– HY-N0173
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H22N2O
References
– [1]Beckman ML, et al. Stereoselective inhibition of serotonin transporters by antimalarial compounds. Neurochem Int. 2014 Jul;73:98-106.
CAS Number
– 485-71-2
Molecular Weight
– 294.39
Compound Purity
– 98.20
SMILES
– C=C[C@H]1C[N@](CC[C@H]1C2)[C@]2([H])[C@H](O)C3=CC=NC4=CC=CC=C34
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)
Target
– Parasite;Serotonin Transporter
Isoform
– Plasmodium
Pathway
– Anti-infection;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.