Cinchonidine

$50$55

Products Details

Product Description

– Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities[1].

Web ID

– HY-N0173

Storage Temperature

– 4°C (Powder, protect from light, stored under nitrogen)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C19H22N2O

References

– [1]Beckman ML, et al. Stereoselective inhibition of serotonin transporters by antimalarial compounds. Neurochem Int. 2014 Jul;73:98-106.

CAS Number

– 485-71-2

Molecular Weight

– 294.39

Compound Purity

– 98.20

SMILES

– C=C[C@H]1C[N@](CC[C@H]1C2)[C@]2([H])[C@H](O)C3=CC=NC4=CC=CC=C34

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 33.33 mg/mL (ultrasonic)

Target

– Parasite;Serotonin Transporter

Isoform

– Plasmodium

Pathway

– Anti-infection;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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