Cholic acid

$60$84

Products Details

Product Description

– Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active[1][2].

Web ID

– HY-N0324

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C24H40O5

References

– [1]Li Y, et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684.|[2]Pan X, et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352.

CAS Number

– 81-25-4

Molecular Weight

– 408.57

Compound Purity

– 98.0

SMILES

– C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C

Clinical Information

– Launched

Research Area

– Metabolic Disease

Solubility

– 0.1 M NaOH : 33.33 mg/mL (ultrasonic;adjust pH to 9 with NaOH)|DMSO : ≥ 50 mg/mL|H2O : 0.67 mg/mL (ultrasonic)

Target

– Endogenous Metabolite

Isoform

– Human Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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