Download Files:
Chlorprothixene
$66 – $238
Products Details
Product Description
– Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].
Web ID
– HY-B0274
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H18ClNS
References
– [1]Y von Coburg, et al. Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorg Med Chem Lett. 2009 Jan 15;19(2):538-42.|[2]B L Roth, et al. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10.
CAS Number
– 113-59-7
Molecular Weight
– 315.86
Compound Purity
– 99.61
SMILES
– CN(C)CC/C=C1C2=C(SC3=C1C=CC=C3)C=CC(Cl)=C2
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)|H2O : 0.67 mg/mL (ultrasonic)
Target
– Bacterial;Dopamine Receptor;Histamine Receptor
Isoform
– D1 Receptor;D2 Receptor;D3 Receptor;D5 Receptor;H1 Receptor
Pathway
– Anti-infection;GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
