CGP52411

SKU T10782-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 56 CAD through 933 CAD

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Product Description

– CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks the toxic influx of Ca2+ ions into neuronal cells and dramatically inhibits and reverses the formation of β-amyloid Aβ42 fibril aggregates. CGP52411 can be used in studies about Alzheimer’s diseases.

Web ID

– T10782

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H15N3O2

References

– Buchdunger E, et al. 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2334-8.

CAS Number

– 145915-58-8

Molecular Weight

– C20H15N3O2

Compound Purity

– 0.9956

SMILES

– O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12

Target

– CDK

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

CGP52411

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