CFSE

SKU T6802-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 83 CAD through 701 CAD

Products Details

Product Description

– CFSE (CFDA-SE) is a fluorescent dye with cell membrane permeability. CFSE irreversibly binds to intracellular proteins in living cells and is used for the detection of cell proliferation. The labeled cells fluoresce in green color with excitation wavelength of 488 nm and emission wavelength of 518 nm.

Web ID

– T6802

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H19NO11

Citations

– 1. Guo E, Xiao R, Wu Y, et al. WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway. Journal of Experimental Medicine. 2021, 219(1): e20210789. 2. Liao Y, Huang J, Liu P, et al. Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer. Oncogene. 2022: 1-13. 3. Xiao C, Su J, Zhang C, et al. Effectiveness of Booster Doses of the SARS-CoV-2 Inactivated Vaccine KCONVAC against the Mutant Strains. Viruses. 2022, 14(9): 2016. 4. Xiao C, Mao L, Wang Z, et al. SARS-CoV-2 variant B. 1.1. 7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. Iscience. 2022 Mar 18;25(3):103934. doi: 10.1016/j.isci.2022.103934. Epub 2022 Feb 17. 5. Deng J, Pan J, Qiu M, et al. Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins. Journal of Leukocyte Biology. 2021 6. Jablonski S, Mou H, Otsuka Y, et al. Identification of Potent Small Molecule Inhibitors of SARS-CoV-2 Entry. SLAS Discovery. 2021 7. Zhao G, Tong Y, Xu J, et al.Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity.Molecular Immunology.2023, 160: 133-149. 8. Xiao C, Ren Z, Zhang B, et al.Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults.Nature Aging.2023: 1-18. 9. Yang L, Wu J, Mei G, et al.Corydalis Saxicola Bunting Total Alkaloid Eliminates Porphyromonas gingivalis strain 33277 Internalized into Macrophages by Inhibition of TLR2.Microbes and Infection.2023: 105244. 10. Li P, Xie Y, Wang J, et al.Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy.Bioactive Materials.2024, 34: 466-481.

References

– Quah BJ, et al. The use of carboxyfluorescein diacetate succinimidyl ester (CFSE) to monitor lymphocyte proliferation. J Vis Exp. 2010 Oct 12;(44):2259.

CAS Number

– 150347-59-4

Molecular Weight

– C29H19NO11

Compound Purity

– 0.9863

SMILES

– CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3cc(ccc23)C(=O)ON2C(=O)CCC2=O)c1.CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3ccc(cc23)C(=O)ON2C(=O)CCC2=O)c1

Pathway

– Others

Product type

– Dye-Reagents

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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