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CDK4/6-IN-2
$350 – $2,650
Products Details
Product Description
– CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1].
Web ID
– HY-114339
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C27H32F2N8
References
– [1]Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.
CAS Number
– 1800506-48-2
Molecular Weight
– 506.59
Compound Purity
– 99.82
SMILES
– CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(C4=CC(N(C(C)C)C(C)=N5)=C5C(F)=C4)=C3)N=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 5.2 mg/mL (ultrasonic)
Target
– CDK
Isoform
– CDK4;CDK6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
