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CCR7 Ligand 1
Price range: 3,085 CAD through 16,320 CAD
Products Details
Product Description
– CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
Web ID
– T10716
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H29N5O5S
References
– Jaeger K, et al. Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7. Cell. 2019 Aug 22;178(5):1222-1230.e10.
CAS Number
– 681514-83-0
Molecular Weight
– C22H29N5O5S
SMILES
– CN(C)C(=O)c1c(C)ccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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