CC-90003

SKU T14894-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 946 CAD

Products Details

Product Description

– CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.

Web ID

– T14894

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H21F3N6O2

Citations

– 1. Jin X, Yang Y, Liu D, et al.Identification of a covalent NEK7 inhibitor to alleviate NLRP3 inflammasome-driven metainflammation.Cell Communication and Signaling.2024, 22(1): 565.

References

– Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.

CAS Number

– 1621999-82-3

Molecular Weight

– C22H21F3N6O2

Compound Purity

– 0.9942

SMILES

– COc1cc(Nc2ncc(c(Nc3ccc(C)cc3NC(=O)C=C)n2)C(F)(F)F)c(C)cn1

Target

– Others

Pathway

– MAPK

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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