Products Details

Product Description

– (+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI2 is an antibody agent conjugates (ADCs) toxin.

Web ID

– HY-128881

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C36H28N6O4

References

– [1]Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.

CAS Number

– 128300-15-2

Molecular Weight

– 608.65

SMILES

– O=C(N1C2=CC=C3NC(C(N4C5=CC=C6NC(C(N7C[C@](C8)([H])[C@]98C%10=CC=CC=C%10C(C=C79)=O)=O)=CC6=C5CC4)=O)=CC3=C2CC1)N

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– ADC Cytotoxin;DNA Alkylator/Crosslinker

Isoform

– Duocarmycins

Pathway

– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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