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(+)-CBI-CDPI1
SKU
HY-128880-Get quote
Category ADC Related
Tags ADC Cytotoxin;DNA Alkylator/Crosslinker, Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage, Cancer
Products Details
Product Description
– (+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. (+)-CBI-CDPI1 is a DNA alkylating agent. (+)-CBI-CDPI1 is an antibody agent conjugates (ADCs) toxin.
Web ID
– HY-128880
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H20N4O3
References
– [1]Boger DL, et al. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity. Bioorg Med Chem. 1994 Feb;2(2):115-35.
CAS Number
– 128300-14-1
Molecular Weight
– 424.45
SMILES
– O=C(N1C2=CC=C3NC(C(N4C[C@](C5)([H])[C@]65C7=CC=CC=C7C(C=C46)=O)=O)=CC3=C2CC1)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin;DNA Alkylator/Crosslinker
Isoform
– Duocarmycins
Pathway
– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.