Catechol O-methyltransferase

$320

Only 1000 item(s) left in stock.

Products Details

Product Description

– Catechol O-methyltransferase (COMT) the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain[1].

Web ID

– HY-E70007

Storage Temperature

– -20°C

Shipping

– Blue Ice

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– N/A

References

– [1]Du X, et, al. A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14.

CAS Number

– 9012-25-3

Molecular Weight

– N/A

SMILES

– [Catechol O-methyltransferase]

Clinical Information

– Phase 2

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Biochemical Assay Reagents

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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