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Catechol O-methyltransferase
SKU
HY-E70007-1 mg
Category Biochemical Assay Reagents
Tags Endogenous Metabolite, Metabolic Enzyme/Protease, Neurological Disease
$320
Only 1000 item(s) left in stock.
Products Details
Product Description
– Catechol O-methyltransferase (COMT) the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain[1].
Web ID
– HY-E70007
Storage Temperature
– -20°C
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– N/A
References
– [1]Du X, et, al. A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14.
CAS Number
– 9012-25-3
Molecular Weight
– N/A
SMILES
– [Catechol O-methyltransferase]
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.