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Carboxyamidotriazole Orotate
Price range: 53 CAD through 910 CAD
Products Details
Product Description
– Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and associated signaling pathways. As the orotate salt form of Carboxyamidotriazole (CAI), it is an orally bioavailable signal transduction inhibitor with in vitro antileukaemic activity, exhibiting anti-tumor, anti-inflammatory, and antiangiogenic effects.
Web ID
– T14871
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H16Cl3N7O6
References
– Corrado C, et al. Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis. PLoS One. 2012;7(8):e42310.
CAS Number
– 187739-60-2
Molecular Weight
– C22H16Cl3N7O6
Compound Purity
– 0.9988
SMILES
– OC(=O)c1cc(=O)[nH]c(=O)[nH]1.NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N
Target
– Others
Pathway
– Membrane transporter/Ion channel|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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