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C215
Products Details
Product Description
– C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages[1].
Web ID
– HY-124814
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H17Cl2N3
References
– [1]Stanley SA, Grant SS, Kawate T, et al. Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening. ACS Chem Biol. 2012;7(8):1377-1384.
CAS Number
– 912780-51-9
Molecular Weight
– 334.24
SMILES
– CCCN1C2=CC=C(NCC3=CC=C(Cl)C=C3Cl)C=C2N=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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