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Bupivacaine (hydrochloride)
$72 – $108
Products Details
Product Description
– Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain[1][2][3].
Web ID
– HY-B0405A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H29ClN2O
Citations
– Sci Rep. 2022 Jan 26;12(1):1378.|Stem Cell Res Ther. 2021 Feb 4;12(1):107.|Nat Commun. 2023 Jun 3;14(1):3224.
References
– [1]Casati A, et, al. Bupivacaine, levobupivacaine and ropivacaine: are they clinically different? Best Pract Res Clin Anaesthesiol. 2005 Jun;19(2):247-68.|[2]Dan J, et, al. Inhibition of gastric cancer by local anesthetic bupivacaine through multiple mechanisms independent of sodium channel blockade. Biomed Pharmacother. 2018 Jul;103:823-828.
CAS Number
– 18010-40-7
Molecular Weight
– 324.89
Compound Purity
– 99.92
SMILES
– O=C(C1N(CCCC)CCCC1)NC2=C(C)C=CC=C2C.Cl
Clinical Information
– Launched
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 25 mg/mL (ultrasonic)|H2O : 12.5 mg/mL (ultrasonic)
Target
– Calcium Channel;iGluR;Potassium Channel;Sodium Channel
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
