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Products Details
Product Description
– BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ[1].
Web ID
– HY-128597
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H25N5O3
References
– [1]Huang L, et al. Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J Med Chem. 2019 May 9;62(9):4526-4542.
CAS Number
– 2351938-32-2
Molecular Weight
– 395.45
SMILES
– CN(C1)C[C@H](NC(N2C)=NC3=C(NC=C3)C2=O)C[C@@H]1C4=CC=C5OCCOC5=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
