Bomedemstat ditosylate

SKU T70008-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 187 CAD through 3,952 CAD

Products Details

Product Description

– Bomedemstat ditosylate (IMG-7289 ditosylate) is an orally active lysine-specific demethylase 1 (LSD1) inhibitor with antitumor activity that potentiates the response to PD-1 inhibition in a homozygous model of SCLC, inhibits cancer cell proliferation, and induces apoptosis. Bomedemstat ditosylate can be used to study myeloproliferative neoplasms and myelofibrosis.

Web ID

– T70008

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C42H50FN7O8S2

References

– Jutzi JS,et al. LSD1 Inhibition Prolongs Survival in Mouse Models of MPN by Selectively Targeting the Disease Clone. Hemasphere. 2018 Jun 8;2(3):e54.

CAS Number

– 1990504-72-7

Molecular Weight

– C42H50FN7O8S2

Compound Purity

– 0.9905

SMILES

– Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.[H][C@]1(C[C@H]1NCCC[C@H](NC(=O)c1ccc(cc1)-n1ccnn1)C(=O)N1CCN(C)CC1)c1ccc(F)cc1

Pathway

– Apoptosis|||Chromatin/Epigenetic

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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