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Products Details
Product Description
– Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2[1][2].
Web ID
– HY-134432A
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C29H43ClN8O8
References
– [1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292.|[2]Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963.
CAS Number
– 201849-55-0
Molecular Weight
– 667.15
SMILES
– CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O.Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
