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BMS-599626 Hydrochloride
Price range: 59 CAD through 1,054 CAD
Products Details
Product Description
– BMS-599626 Hydrochloride (AC480 Hydrochloride) is an orally bioavailable inhibitor of the HER1, HER2, and HER4 tyrosine kinases (IC50 = 22, 32, and 190 nM, respectively) with potential antineoplastic activity, inhibiting the proliferation of tumor cells that overexpress these receptors.
Web ID
– T5390
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H28ClFN8O3
References
– Wong TW, et al. Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6186-93.
CAS Number
– 873837-23-1
Molecular Weight
– C27H28ClFN8O3
Compound Purity
– 1
SMILES
– Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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