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Bleomycin Sulfate
Price range: 59 CAD through 1,160 CAD
Products Details
Product Description
– Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
Web ID
– T6116
Storage Temperature
– -20℃
Shipping
– Blue Ice
Citations
– 1. Yi X M, Li M, Chen Y D, et al. Reciprocal regulation of IL-33 receptor–mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38. Proceedings of the National Academy of Sciences. 2022, 119(10): e2116279119
2. Liang J, Niu Z, Zhang B, et al. p53-dependent elimination of aneuploid mitotic offspring by entosis. Cell Death & Differentiation. 2020: 1-15
3. Liang J, Niu Z, Zhang B, et al Liang J, Niu Z, Zhang B, et al. p53-dependent elimination of aneuploid mitotic offspring by entosis. Cell Death & Differentiation. 2020: 1-15.
4. Wang T, Shi S, Shi Y, et al.Chemical-induced phase transition and global conformational reorganization of chromatin.Nature Communications.2023, 14(1): 5556.
5. Chen Y, Wang T, Liang F, et al.Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice.Theranostics.2024, 14(7): 2794.
6. Li R, Li Y, Jiang K, et al.Lighting up arginine metabolism reveals its functional diversity in physiology and pathology.Cell Metabolism.2024
7. Yang W, Yuan H, Sun H, et al.Co-Mn Complex Oxide Nanoparticles as Potential Reactive Oxygen Species Scavenging Agents for Pulmonary Fibrosis Treatment.Molecules.2024, 29(21): 5106.
References
– Sakharkar MK, et al. Key drug-targeting genes in pancreatic ductal adenocarcinoma. Genes Cancer. 2021 Mar 11;12:12-24.
CAS Number
– 9041-93-4
Molecular Weight
Compound Purity
– ≥98%
Pathway
– Microbiology/Virology|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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