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Bis-PEG5-NHS ester
SKU
HY-126889-100 mg
Category ADC Related
Tags ADC Linker;PROTAC Linkers, Antibody-drug Conjugate/ADC Related;PROTAC, Cancer
$36 – $92
Products Details
Product Description
– Bis-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-126889
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H32N2O13
References
– [1]Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. WO2018114798A1.
CAS Number
– 756526-03-1
Molecular Weight
– 532.50
Compound Purity
– 97.0
SMILES
– O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Alkyl/ether Linkers;Cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.