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Product Description
– Biotin-(L-Thyroxine) is the biotinylated L-Thyroxine (HY-18341). L-Thyroxine is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from Biotin-(L-Thyroxine) (T4)[1].
Web ID
– HY-18341F
Shipping
– Room temperature
Molecular Formula
– C25H25I4N3O6S
References
– [1]Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323.|[2]Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149.
CAS Number
– 149734-00-9
Molecular Weight
– 1003.17
SMILES
– IC(C=C1C[C@@H](C(O)=O)NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=C(C(I)=C1)OC4=CC(I)=C(C(I)=C4)O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;Thyroid Hormone Receptor
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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