Bicuculline

SKU T2850-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 101 CAD

Products Details

Product Description

– Bicuculline ((+)-Bicuculline) is a light-sensitive competitive antagonist of GABAA receptors, originally identified in 1932 from plant alkaloid extracts, and isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and various Corydalis species.

Web ID

– T2850

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H17NO6

Citations

– 1. Huang C, Dong C, Zhu Y, et al. Duhaldea pterocaula (Franch.) Anderb. Attenuates Nociception and Inflammation via GABAA Receptors. Frontiers in Pharmacology. 2021: 3086. 2. Li L, Kang Y, Cheng R, et al.The de novo synthesis of GABA and its gene regulatory function control hepatocellular carcinoma metastasis.Developmental Cell.2024

References

– Huang SH, et al. Eur J Pharmacol, 2003, 464(1), 1-8.

CAS Number

– 485-49-4

Molecular Weight

– C20H17NO6

Compound Purity

– 0.9999

SMILES

– [H][C@]1(OC(=O)c2c3OCOc3ccc12)[C@@]1([H])N(C)CCc2cc3OCOc3cc12

Pathway

– Membrane transporter/Ion channel|||Neuroscience

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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