BGG463
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BGG463

SKU T4618-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 90 CAD through 1,229 CAD

Products Details

Product Description

– BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.

Web ID

– T4618

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H29F3N6O3

Citations

– 1. Jiang L, Yu Y, Li Z, et al.BMS-265246, a Cyclin-Dependent Kinase Inhibitor, Inhibits the Infection of Herpes Simplex Virus Type 1.Viruses.2023, 15(8): 1642.

References

– Alexander LT, et al. Type II Inhibitors Targeting CDK2. ACS Chem Biol. 2015 Sep 18;10(9):2116-25.

CAS Number

– 890129-26-7

Molecular Weight

– C30H29F3N6O3

Compound Purity

– 0.9505

SMILES

– CN1CCN(Cc2ccc(NC(=O)c3cccc4cc(Oc5cc(NC(C)=O)ncn5)ccc34)cc2C(F)(F)F)CC1

Pathway

– Angiogenesis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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