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Products Details
Product Description
– BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64, 0.25 nM for BRD4-BD1, BRD4-BD2, respectively. BET-IN-15 shows antiproliferative activity[1].
Web ID
– HY-153945
Shipping
– Room temperature
Molecular Formula
– C21H18F2N4O3S
References
– [1]WenWei Xu, et al. Crystal form and salt form of bromine domain protein inhibitor and preparation method therefor. WO2021143922A1.
CAS Number
– 2408994-22-7
Molecular Weight
– 444.45
SMILES
– O=C1C2=C(C(C3=C(OC4=CC=C(C=C4F)F)C=CC(N=S(C)(C)=O)=N3)=CN1C)C=CN2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
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